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Double Marker Test Booking, Procedure, and Results [2022-23]

Dr Abhishtita MundunuriLast Updated on 29th November 2021

The Double Marker Test is a part of the first-trimester screening procedure. It is also called maternal serum screening that helps check for chromosomal abnormalities in a developing foetus.

What is the Double Marker Test used for?What is included in a Double Marker Test?Double Marker Test Procedure How to prepare for the Double Marker Test? What types of diseases can a Double Marker Test Test detect?How much risk is involved?How long does it take to get the Double Marker Test results?What affects the Double Marker Test results?Frequently Asked Questions | FAQs

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What is the Double Marker Test used for?

A Double Marker Test is a blood test used to check for chromosomal abnormalities in a developing foetus.
Human beings have 23 pairs of chromosomes (one from the father and one from the mother to make up a pair). Each pair is labelled as chromosome 1, chromosome 2, chromosome 3 and so on through chromosome 23.
Any fewer or extra chromosomes lead to genetic abnormalities in the progeny:
Down’s syndrome is a genetic abnormality wherein there’s an extra copy of chromosome 21.
An extra copy of chromosome 18 causes Edward’s syndrome.
An extra copy of chromosome 13 causes Patau’s syndrome.
A Double Marker Test helps detect Down’s syndrome, Edward’s syndrome and Patau’s syndrome in a developing foetus.

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What is included in a Double Marker Test?

This test screens for levels of beta-human gonadotropin (beta-hCG) and Pregnancy Associated Plasma Protein A (PAPP-A) in the blood; abnormal levels of these markers in the blood predict genetic abnormalities in the developing foetus.

Sample required for the test

This test involves a simple blood test.

Double Marker Test Procedure

The procedure for this test involves a blood test that does not require any fasting.

Download the MFine app now to book an online consultation with a specialist doctor. You can also get lab tests done at home and order medicines through the MFine app.

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How to prepare for the Double Marker Test?

Before the Test	During the Test
The blood test and ultrasound is a pretty simple procedure. The blood test does not require a fast.	The lab technician will sanitize the affected location to draw the blood sample; you may feel pain, but the entire procedure is over quickly.

Things to consider after the Double Marker Test is completed?

You need to consult with your doctor, who will suggest the best way as you advance in your pregnancy.

What types of diseases can a Double Marker Test Test detect?

Down’s syndrome
Edward’s syndrome
Patau’s syndrome

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How much risk is involved?

The blood test is a safe procedure. There are no known risks.

How long does it take to get the Double Marker Test results?

Your blood report will be updated on the MFine app within the next 3-4 days after blood sample collection. This test takes longer to report compared to most other blood tests.

Is the Double Marker Test a definitive test?

Double Marker Test is a predictive test meaning the test reports the likelihood of chromosomal abnormalities.

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How to read the Double Marker Test report?

After the blood test, your doctor will discuss the results with you later and advise you on what needs to be done for a healthy pregnancy. If the results are abnormal, the doctor will discuss the results with you and may advise a Noninvasive Prenatal Testing like amniocentesis.

What affects the Double Marker Test results?

A Double Marker Test involves a simple blood test taken in a non fasting state. Consult a doctor beforehand for best results.

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Where to get the Double Marker Test done?

Book Double Marker Test online from certified lab partners in your city through the MFine app and get the test done at home.

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Frequently Asked Questions | FAQs

Is fasting required for a Double Marker Test?

The double Marker blood test does not require fasting.

How accurate is a Double Marker Test?

Double Marker Test has a high success rate in determining Down’s Syndrome and is recommended by doctors worldwide.

When to take a Double Marker Test?

This test is performed between the 10th and 13th week of pregnancy.

What if the Double Marker Test is missed?

If you miss the dates for this test, you may opt for a triple or quad test later on. Kindly consult your doctor.

What is the normal range for PAPP-A?

A PAPP-A level of 0.5 MOM and above is considered normal.

Does low PAPP-A always mean Down's Syndrome?

Double Marker Test is a predictive test, meaning they only predict genetic abnormalities. Kindly consult with your doctor if you have low PAPP-A levels.